Anaesthesia and emesis. Clinical usefulness of metoclopramide

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Anaesthesia and emesis. Clinical usefulness of metoclopramide.

To the Editor: In the otherwise excellent review article "Anaesthesia and emesis, II" by Palazzo and Strunin, ~ the section devoted to metoclopramide is perhaps open to comment. Reference is made to Davies and Howells' paper on the ability of metoclopramide to empty the stomach following injury, 2 which did not differentiate between liquid and solid gastric content. Hancock 3 showed no differen...

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Evaluation of prochlorperazine buccal tablets (Bukatel) and metoclopramide oral tablets in the treatment of acute emesis.

The dizziness associated with vertiginous disorders is often accompanied with nausea and/or vomiting. Antiemetic effect of prochlorperazine (PCZ) is diminished by its low bioavailability owing to a significant gastric and hepatic first pass effect. This effect could be further diminished by likelihood of regurgitation of nauseating patients further limiting the therapeutic effect of oral PCZ. A...

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Propofol anaesthesia reduces early postoperative emesis after paediatric strabismus surgery.

Propofol anaesthesia may reduce postoperative emesis. The purpose of this study was to compare the incidence of emesis after propofol anaesthesia with and without nitrous oxide, compared with thiopentone and halothane anaesthesia, in hospital and up to 24 hr postoperatively, in outpatient paediatric patients after strabismus surgery. Seventy-five ASA class I or II, unpremedicated patients, aged...

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Randomised comparison of ondansetron and metoclopramide plus dexamethasone for chemotherapy induced emesis.

The serotonin (5HT3) antagonist ondansetron was compared in a randomised study with metoclopramide and dexamethasone for the prevention of chemotherapy induced emesis. Thirty children aged 1-15 years with acute lymphoblastic leukaemia received 'intensification modules' according to the MRC United Kingdom acute lymphoblastic leukaemia regimen UKALL XI. This contains the moderately emetogenic dru...

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ژورنال

عنوان ژورنال: Canadian Anaesthetists’ Society Journal

سال: 1985

ISSN: 0008-2856,1496-8975

DOI: 10.1007/bf03010053